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Merck
CN

SML3267

Nardosinone

≥98% (HPLC)

Synonym(s):

(3aR,9R,9aR,9bS)-1,3a,4,7,8,9,9a,9b-Octahydro-1,1,9,9a-tetramethyl-5H-naphtho[2,1-c][1,2]dioxol-5-one, Nardosinon

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About This Item

Empirical Formula (Hill Notation):
C15H22O3
CAS Number:
Molecular Weight:
250.33
UNSPSC Code:
12352200
MDL number:
NACRES:
NA.21
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SMILES string

O1OC([C@@H]2[C@H]1CC(=O)C3=CCC[C@H]([C@@]32C)C)(C)C

InChI

1S/C15H22O3/c1-9-6-5-7-10-11(16)8-12-13(15(9,10)4)14(2,3)18-17-12/h7,9,12-13H,5-6,8H2,1-4H3/t9-,12-,13+,15+/m1/s1

InChI key

KXGHHSIMRWPVQM-JWFUOXDNSA-N

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

Quality Level

Biochem/physiol Actions

Main active ingredient from medical plant Nardostachys jatamansi; anti-inflammatory and anti-hypertrophic in cardiomyocytes
Nardosinone is a main active ingredient from medical plant Nardostachys jatamansi. Nardosinone exhibits varies pharmacological effects including anti-inflammatory and anti-hypertrophic in cardiomyocytes. Nardosinone enhances activity of the nerve growth factor and promotes neural stem cells proliferation and differentiation. The molecular mechanism of its activity remains unclear.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

监管及禁止进口产品
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