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Merck
CN

SML3267

Sigma-Aldrich

Nardosinone

≥98% (HPLC)

Synonym(s):

(3aR,9R,9aR,9bS)-1,3a,4,7,8,9,9a,9b-Octahydro-1,1,9,9a-tetramethyl-5H-naphtho[2,1-c][1,2]dioxol-5-one, Nardosinon

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About This Item

Empirical Formula (Hill Notation):
C15H22O3
CAS Number:
23720-80-1
Molecular Weight:
250.33
MDL number:
MFCD21363103
UNSPSC Code:
12352200

Key Documents

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Quality Level

100

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

O1OC([C@@H]2[C@H]1CC(=O)C3=CCC[C@H]([C@@]32C)C)(C)C

InChI

1S/C15H22O3/c1-9-6-5-7-10-11(16)8-12-13(15(9,10)4)14(2,3)18-17-12/h7,9,12-13H,5-6,8H2,1-4H3/t9-,12-,13+,15+/m1/s1

InChI key

KXGHHSIMRWPVQM-JWFUOXDNSA-N

Biochem/physiol Actions

Main active ingredient from medical plant Nardostachys jatamansi; anti-inflammatory and anti-hypertrophic in cardiomyocytes
Nardosinone is a main active ingredient from medical plant Nardostachys jatamansi. Nardosinone exhibits varies pharmacological effects including anti-inflammatory and anti-hypertrophic in cardiomyocytes. Nardosinone enhances activity of the nerve growth factor and promotes neural stem cells proliferation and differentiation. The molecular mechanism of its activity remains unclear.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

监管及禁止进口产品

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Certificates of Analysis (COA)

Lot/Batch Number
0000185601
0000185602
0000166054
0000185601
0000185602

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