SML3284
MS1943
≥98% (HPLC)
Synonym(s):
N-[(1,2-Dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-1-(1-methylethyl)-6-[6-[4-[2-[(2-tricyclo[3.3.1.13,7]dec-1-ylacetyl)amino]ethyl]-1-piperazinyl]-3-pyridinyl]-1H-indazole-4-carboxamide
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About This Item
Empirical Formula (Hill Notation):
C42H54N8O3
CAS Number:
Molecular Weight:
718.93
UNSPSC Code:
12352200
NACRES:
NA.77
Quality Level
Assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear (Warmed)
storage temp.
2-8°C
Biochem/physiol Actions
MS1943 is a potent and selective degrader of EZH2 (enhancer of zeste homolog 2) that effectively reduces EZH2 levels in cells. MS1943 potently inhibits growth of multiple TNBC cells and in mice xenograft model.
Potent and selective degrader of EZH2 (enhancer of zeste homolog 2) that effectively reduces EZH2 levels in cells.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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