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CN

SML3286

cUMP sodium salt

≥98% (HPLC)

Synonym(s):

3’,5’-cyclic uridine monophosphate sodium salt, CID 3081385 sodium, Uridine cyclic 3′,5′-monophosphate monosodium salt, cyclic UMP sodium

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About This Item

Empirical Formula (Hill Notation):
C9H10N2O8P·Na
CAS Number:
56632-58-7
Molecular Weight:
328.15
UNSPSC Code:
12352200
NACRES:
NA.32
MDL number:
MFCD00134914

Key Documents

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Product Name

cUMP sodium salt, ≥98% (HPLC)

InChI

1S/C9H11N2O8P.Na/c12-5-1-2-11(9(14)10-5)8-6(13)7-4(18-8)3-17-20(15,16)19-7;/h1-2,4,6-8,13H,3H2,(H,15,16)(H,10,12,14);/q;+1/p-1

SMILES string

O[C@H]1[C@@](N2C(NC(C=C2)=O)=O)([H])O[C@@]3([H])[C@@]1([H])OP(OC3)(O[Na])=O

InChI key

APYWIKXPIFYSBG-UHFFFAOYSA-M

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

−20°C

Quality Level

100

General description

3’,5’-cyclic uridine monophosphate (cUMP) is a cyclic pyrimidine nucleotide. cUMP (3’,5’-cyclic uridine monophosphate) sodium salt is a secondary messenger functioning in bacterial immunity against viruses.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
0000166316
0000166316

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Molecular neurobiology, 58(5), 2435-2446 (2021-01-14)
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Nicole Blaquiere et al.
Journal of medicinal chemistry, 61(15), 6801-6813 (2018-06-26)
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Sander de Kivit et al.
Nature metabolism, 2(10), 1046-1061 (2020-09-23)
Following activation, conventional T (Tconv) cells undergo an mTOR-driven glycolytic switch. Regulatory T (Treg) cells reportedly repress the mTOR pathway and avoid glycolysis. However, here we demonstrate that human thymus-derived Treg (tTreg) cells can become glycolytic in response to tumour
Hans D Brightbill et al.
Nature communications, 9(1), 179-179 (2018-01-14)
NF-κB-inducing kinase (NIK) mediates non-canonical NF-κB signaling downstream of multiple TNF family members, including BAFF, TWEAK, CD40, and OX40, which are implicated in the pathogenesis of systemic lupus erythematosus (SLE). Here, we show that experimental lupus in NZB/W F1 mice
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