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About This Item
Empirical Formula (Hill Notation):
C25H24N2O4
CAS Number:
Molecular Weight:
416.47
UNSPSC Code:
12352200
MDL number:
Quality Level
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
O=C(C1=CC=C(CNC(C=C)=O)C=C1)NC2=C(OC3=CC=C(OCC)C=C3)C=CC=C2
InChI
1S/C25H24N2O4/c1-3-24(28)26-17-18-9-11-19(12-10-18)25(29)27-22-7-5-6-8-23(22)31-21-15-13-20(14-16-21)30-4-2/h3,5-16H,1,4,17H2,2H3,(H,26,28)(H,27,29)
InChI key
DKOWGKKELPCHEG-UHFFFAOYSA-N
Biochem/physiol Actions
Cell penetrant, potent and selective covalent c-MYC inhibitor that targets cysteine 171
EN4 is a cell penetrant, potent and selective covalent c-MYC inhibitor that targets cysteine 171 located within a predicted intrinsically disordered region of MYC. EN4 inhibits MYC transcriptional activity, downregulates multiple MYC transcriptional targets, reduces MYC and MAX thermal stability, and impairs tumorigenesis.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| SML3290-25MG | 04065267176734 |
| SML3290-5MG | 04065267176741 |
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