SML3304
TP-040n
≥98% (HPLC)
Synonym(s):
4-(4-Methyl-1-piperazinyl)-N-(2-phenylethyl)-2-pyrimidinamine
Sign Into View Organizational & Contract Pricing
Select a Size
About This Item
Empirical Formula (Hill Notation):
C17H23N5
CAS Number:
Molecular Weight:
297.40
UNSPSC Code:
12352200
NACRES:
NA.77
Quality Level
Assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
CN1CCN(C2=CC=NC(NCCC3=CC=CC=C3)=N2)CC1
InChI
1S/C17H23N5/c1-21-11-13-22(14-12-21)16-8-10-19-17(20-16)18-9-7-15-5-3-2-4-6-15/h2-6,8,10H,7,9,11-14H2,1H3,(H,18,19,20)
InChI key
BNXNWRSVYQHTOH-UHFFFAOYSA-N
Related Categories
Biochem/physiol Actions
Inactive control for TP-040 a brain penetrant, potent and selective inhibitor of O-GlcNAcase (OGA)
TP-040n is an inactive control for TP-040 a brain penetrant, potent and selective inhibitor of O-GlcNAcase (OGA).
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
新产品
This item has
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Michiko Tawada et al.
Journal of medicinal chemistry, 64(2), 1103-1115 (2021-01-07)
O-GlcNAcase (OGA) has received increasing attention as an attractive therapeutic target for tau-mediated neurodegenerative disorders; however, its role in these pathologies remains unclear. Therefore, potent chemical tools with favorable pharmacokinetic profiles are desirable to characterize this enzyme. Herein, we report
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service