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Merck
CN

SML3345

LSL 60101

≥98% (HPLC)

Synonym(s):

2-(1-Benzofuran-2-yl)-1H -imidazole, 2-(2-Benzofuranyl)-1H -imidazole (ACI), Garsevil, LSL60101

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About This Item

Empirical Formula (Hill Notation):
C11H8N2O
CAS Number:
Molecular Weight:
184.19
UNSPSC Code:
51111800
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Quality level:
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SMILES string

[nH]1c(ncc1)c2[o]c3c(c2)cccc3

InChI

1S/C11H8N2O/c1-2-4-9-8(3-1)7-10(14-9)11-12-5-6-13-11/h1-7H,(H,12,13)

InChI key

VBFQIUOSXHUWCT-UHFFFAOYSA-N

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

Quality Level

Biochem/physiol Actions

LSL 60101 is an orally available, potent and selective I2 imidazoline receptor ligand that induces morphological/biochemical changes in astroglia and exhibits neuroprotective activity. LSL 60101 decreases neuroinflammation and reverses cognitive deficits and impaired social behavior in 5XFAD mice Alzheimer’s model.
Orally available, potent and selective I2 imidazoline receptor ligand that exhibits neuroprotective activity

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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