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Merck
CN

SML3356

Gefarnate

≥98% (HPLC)

别名:

(4E,​8E)​-5,​9,​13-​Trimethyl-​4,​8,​12-​tetradecatrienoic acid (2E)​-​3,​7-​dimethyl-​2,​6-​octadien-​1-​yl ester, (E,E,E)-4,8,12-Tetradecatrienoic acid, 5,9,13-trimetyl-, 3,7-dimetyl-2,6-octadienyl ester, Geranyl farnesylacetate

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关于此项目

经验公式(希尔记法):
C27H44O2
化学文摘社编号:
分子量:
400.64
UNSPSC Code:
51111800
MDL number:
Assay:
≥98% (HPLC)
Form:
liquid
Storage condition:
desiccated
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Quality Segment

assay

≥98% (HPLC)

form

liquid

storage condition

desiccated

color

colorless to beige

storage temp.

−20°C

SMILES string

CC(C)=CCC/C(C)=C/COC(CC/C=C(CC/C=C(CCC=C(C)C)\C)\C)=O

InChI

1S/C27H44O2/c1-22(2)12-8-14-24(5)16-10-17-25(6)18-11-19-27(28)29-21-20-26(7)15-9-13-23(3)4/h12-13,16,18,20H,8-11,14-15,17,19,21H2,1-7H3/b24-16+,25-18+,26-20+

InChI key

ZPACYDRSPFRDHO-ROBAGEODSA-N

Biochem/physiol Actions

Anti-ulcer drug that stimulates gastric mucin secretion
Gefarnate is an anti-ulcer drug that stimulates gastric mucin secretion. Also gefarnate increase secretion of mucin-like glycoprotein in rabbit conjunctival tissue. It appears to be effective in animal dry-eye models. It is approved in Japan, where it is used to treat gastritis and gastric ulcer. Gefarnate is structurally similar to anti-ulcer drug teprenone (geranyl farnesylacetate), which induces expression of HSP70, HSPB8, and HSPB1.


存储类别

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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