SML3372
Glutipyran
≥98% (HPLC)
Synonym(s):
rel-N-(3,4-Dimethoxybenzyl)-N-((R)-3-((S)-2,2-dimethyltetrahydro-2H-pyran-4-yl)-3-phenylpropyl)furan-2-carboxamide
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About This Item
Empirical Formula (Hill Notation):
C30H37NO5
Molecular Weight:
491.62
UNSPSC Code:
12352200
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
Quality Segment
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to beige
solubility
DMSO: 2 mg/mL, clear
shipped in
dry ice
storage temp.
-10 to -25°C
Biochem/physiol Actions
Glutipyran is a broad-spectrum potent and selective glucose transporter (GLUT) inhibitor that targets both GLUT1 and GLUT3. Glutipyran inhibits glycolytic activity and cell growth in PANC-1 cells (IC50 = 1.9 µM). It exhibits antitumor activity (12.5 mg/kg, i.v.) once daily in MIA PaCa-2 xenograft mouse model.
Broad-spectrum potent and selective glucose transporter (GLUT) inhibitor
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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