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Merck
CN

SML3377

BG-3

≥98% (HPLC)

Synonym(s):

N-(4-Chlorophenyl)-6-ethyl-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-amine, SID 124738112

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About This Item

Empirical Formula (Hill Notation):
C14H14ClN5
CAS Number:
Molecular Weight:
287.75
UNSPSC Code:
51111800
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

CC1=NC2=NC=NN2C(NC3=CC=C(Cl)C=C3)=C1CC

Biochem/physiol Actions

BG-3 is a cell penetrant, potent and selective inhibitor of Pax2 (paired-box 2) that inhibits Pax2 transactivation ability. BG-3 inhibit the ability of Pax proteins to recruit PTIP and promote H3K4 methylation at Pax binding sites. BG-3 is not cytotoxic.
cell penetrant, potent and selective inhibitor of Pax2 that inhibits Pax2 transactivation ability


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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