SML3381
10-Hydroxy-trans-2-decenoic acid
≥98% (HPLC), osteoclastogenesis inhibitor, powder
Synonym(s):
(E)-10-Hydroxy-2-decenoic acid, 10-HAD, NSC 87516, Royal jelly acid, Trans-10-hydroxy-2-decenoic acid
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About This Item
Empirical Formula (Hill Notation):
C10H18O3
CAS Number:
Molecular Weight:
186.25
UNSPSC Code:
12352106
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Product Name
10-Hydroxy-trans-2-decenoic acid, ≥98% (HPLC)
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
−20°C
SMILES string
OCCCCCCC\C=C\C(=O)O
InChI
1S/C10H18O3/c11-9-7-5-3-1-2-4-6-8-10(12)13/h6,8,11H,1-5,7,9H2,(H,12,13)/b8-6+
InChI key
QHBZHVUGQROELI-SOFGYWHQSA-N
Biochem/physiol Actions
10-Hydroxy-2-decenoic acid is an orally available royal jelly component that potently inhibits osteoclastogenesis. It binds to free fatty acid receptor 4 (FFAR4) on osteoclasts which inhibits RANKL (receptor activator of nuclear factor-κB (NF-κB) ligand), thereby attenuating the induction of nuclear factor of activated T cells (NFAT) c1. 10-Hydroxy-2-decenoic acid inhibits bone resorption in ovariectomized mice.
Royal jelly component that potently inhibits osteoclastogenesis
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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