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SML3391

Glatiramer acetate

≥95% (HPLC), Myelin basic protein mimetic, powder or Lyophilized powder or film

Synonym(s):

Cop 1 (polyamide), Cop-1, Copaxone, Copolymer 1, GA, Polymer with L-alanine, L-lysine, L-tyrosine, and L-glutamic acid acetate

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About This Item

Linear Formula:
(C9H11NO3)a·(C6H14N2O2)b ·(C5H9NO4)c ·(C3H7NO2)d ·x(CH3CO2H)
UNSPSC Code:
12352200
NACRES:
NA.21
Assay:
≥95% (HPLC)
Form:
(Powder or Lyophilized powder or film)
Storage condition:
desiccated
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Product Name

Glatiramer acetate, ≥95% (HPLC)

Quality Segment

100

assay

≥95% (HPLC)

form

(Powder or Lyophilized powder or film)

storage condition

desiccated

color

white to beige

storage temp.

-10 to -25°C

SMILES string

OC([C@@H](N)C)=O.OC(CC[C@H](N)C(O)=O)=O.NCCCC[C@H](N)C(O)=O.OC([C@@H](N)CC1=CC=C(C=C1)O)=O

InChI

1S/C9H11NO3.C6H14N2O2.C5H9NO4.C3H7NO2/c10-8(9(12)13)5-6-1-3-7(11)4-2-6;7-4-2-1-3-5(8)6(9)10;6-3(5(9)10)1-2-4(7)8;1-2(4)3(5)6/h1-4,8,11H,5,10H2,(H,12,13);5H,1-4,7-8H2,(H,9,10);3H,1-2,6H2,(H,7,8)(H,9,10);2H,4H2,1H3,(H,5,6)/t8-;5-;3-;2-/m0000/s1

InChI key

YLOCGHYTXIINAI-XKUOMLDTSA-N

Biochem/physiol Actions

Glatiramer acetate, a myelin basic protein mimetic, is an immunomodulator used for treatment of Multiple Sclerosis. Glatiramer acetate is a mixture of synthetic peptides randomly composed of glutamic acid, lysine, alanine, and tyrosine. It reduces relapse rate and disease progression in Multiple Sclerosis. Its mechanism of action is not fully understood. Glatiramer acetate generates anti-inflammatory Th2 cells, which produce neurotrophic factors.
Myelin basic protein mimetic; immunodmodulator; used to treat multiple sclerosis; generates anti-inflammatory Th2 cells, which produce neurotrophic factors; promotes neurogenesis

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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