SML3401
NVP-LMD194
≥98% (HPLC)
Synonym(s):
N-[(6-Amino-3-pyridinyl)methyl]-N′-[4-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)methyl]phenyl]urea
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About This Item
Empirical Formula (Hill Notation):
C22H19N5O3
CAS Number:
Molecular Weight:
401.42
NACRES:
NA.77
UNSPSC Code:
12352200
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear (Warmed)
storage temp.
2-8°C
Quality Level
Related Categories
Biochem/physiol Actions
Cellularly active, potent, and selective inhibitor of NAMPT (nicotinamide phosphoribosyltransferase)
NVP-LMD194 is a cellularly active, potent, and selective inhibitor of NAMPT (nicotinamide phosphoribosyltransferase). NVP-LMD194 decreases the viability of A2780 and CORL23 cells.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Structure based design of nicotinamide phosphoribosyltransferase (NAMPT) inhibitors from a phenotypic screen
Bioorganic & Medicinal Chemistry Letters, 28(3), 365-370 (2018)
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