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SML3427

C4-HSL

Name: C4-HSL
Brand: SIGMA

≥95% (HPLC), Autophagy inhibitor, powder

Synonym(s):

(S)-N-(2-Oxotetrahydrofuran-3-yl)butyramide, BHL, N-Butanoyl-L-homoserine lactone, N-Butyrylhomoserine lactone, N-[(3S)-Tetrahydro-2-oxo-3-furanyl]butanamide

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About This Item

Empirical Formula (Hill Notation):

C₈H₁₃NO₃

CAS Number:

67605-85-0

Molecular Weight:

171.19

NACRES:

NA.77

UNSPSC Code:

12352200

MDL number:

MFCD12912262

Assay:

≥95% (HPLC)

Form:

powder

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Properties

Product Name

C4-HSL, ≥95% (HPLC)

Quality Segment

100

assay

≥95% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

−20°C

SMILES string

CCCC(N[C@@H]1C(OCC1)=O)=O

InChI

1S/C8H13NO3/c1-2-3-7(10)9-6-4-5-12-8(6)11/h6H,2-5H2,1H3,(H,9,10)/t6-/m0/s1

InChI key

VFFNZZXXTGXBOG-LURJTMIESA-N

Description

Biochem/physiol Actions

C4-HSL (N-butyryl-L-Homoserine lactone) is a quorum-sensing signaling molecule produced by Pseudomonas aeruginosa. C4-HSL induces expression of the virulence genes lasB and rhlA in P. aeruginosa when used at a concentration of 10 µM. C4-HSL exhibits antibacterial activity against MDR S. aureus isolates but had no effect on A. baumannii.

Quorum-sensing signaling molecule produced by Pseudomonas aeruginosa

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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