SML3455
Idalopirdine
≥98% (HPLC)
Synonym(s):
2-(6-fluoro-1H-indol-3-yl)-ethyl]-[3-(2,2,3,3-tetrafluoropropoxy)-benzyl]-amine, 6-Fluoro-N-[[3-(2,2,3,3-tetrafluoropropoxy)phenyl]methyl]-1H-indole-3-ethanamine, Lu AE58054
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About This Item
Empirical Formula (Hill Notation):
C20H19F5N2O
CAS Number:
Molecular Weight:
398.37
UNSPSC Code:
51111800
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
-10 to -25°C
SMILES string
FC(F)(C(F)F)COc1cc(ccc1)CNCCc2c3c([nH]c2)cc(cc3)F
InChI
1S/C20H19F5N2O/c21-15-4-5-17-14(11-27-18(17)9-15)6-7-26-10-13-2-1-3-16(8-13)28-12-20(24,25)19(22)23/h1-5,8-9,11,19,26-27H,6-7,10,12H2
InChI key
YBAWYTYNMZWMMJ-UHFFFAOYSA-N
Biochem/physiol Actions
Idalopirdine (Lu AE58054) is an orally available, and potent antagonist of the serotonin 6 (5-HT6) receptor. Idalopirdine has been reported to be highly selective over other G-protein coupled receptors. It has K(d) of 0.2nM for the 5-HT6 receptor with 16-fold selectivity over the 5-HT2A receptor (K(i) 3.2nM) and >100-fold selectivity to all other evaluated targets.
Orally available, selective and potent antagonist of the serotonin 6 (5-HT6) receptor.
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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