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SML3479

Hydroxy-α-sanshool

≥95% (HPLC)

Synonym(s):

(2E,6Z,8E,10E)-N-(2-Hydroxy-2-methylpropyl)-2,6,8,10-dodecatetraenamide, 2E,6Z,8E,10E-Dodecatetraenoic acid N-(2-hydroxy-2-methylpropyl)amide

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About This Item

Empirical Formula (Hill Notation):
C16H25NO2
CAS Number:
Molecular Weight:
263.38
UNSPSC Code:
51111800
NACRES:
NA.77
MDL number:
Assay:
≥95% (HPLC)
Form:
powder
Storage condition:
protect from light, under inert gas
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Quality Segment

assay

≥95% (HPLC)

form

powder

storage condition

protect from light, under inert gas

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

-10 to -25°C

SMILES string

N(CC(O)(C)C)C(=O)\C=C\CC\C=C/C=C/C=C/C

InChI

1S/C16H25NO2/c1-4-5-6-7-8-9-10-11-12-13-15(18)17-14-16(2,3)19/h4-9,12-13,19H,10-11,14H2,1-3H3,(H,17,18)/b5-4+,7-6+,9-8-,13-12+

InChI key

LHFKHAVGGJJQFF-UEOYEZOQSA-N

Biochem/physiol Actions

Hydroxy-α-sanshool is an active ingredient in Szechuan peppers (also present in other Zanthoxylum plants) that produces a tingling paresthesia or numbing effects. Hydroxy-α-sanshool is a potent agonist of TRPV1/TRPA1 as well as antagonist/blocker of KCNK3/KCNK9/KCNK18 channels. It induces colonic motor activity in rat proximal colon.
Potent agonist of TRPV1/TRPA1 as well as antagonist/blocker of KCNK3/KCNK9/KCNK18 channels


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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