SML3487
X4-2
≥98% (HPLC)
Synonym(s):
(Cycloheptanecarbonyl)-L-phenylalanine, N -(Cycloheptylcarbonyl)-L-phenylalanine
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About This Item
Empirical Formula (Hill Notation):
C17H23NO3
CAS Number:
Molecular Weight:
289.37
NACRES:
NA.77
UNSPSC Code:
12352200
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
room temp
Quality Level
Biochem/physiol Actions
Inactive control probe for MS47134, which is a selective agonist probe of the GPCR orphan receptor MRGPRX4
X4-2 is an inactive control probe for MS47134, which is a selective agonist probe of the GPCR orphan receptor MRGPRX4.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Can Cao et al.
Nature, 600(7887), 170-175 (2021-11-19)
The MRGPRX family of receptors (MRGPRX1-4) is a family of mas-related G-protein-coupled receptors that have evolved relatively recently1. Of these, MRGPRX2 and MRGPRX4 are key physiological and pathological mediators of itch and related mast cell-mediated hypersensitivity reactions2-5. MRGPRX2 couples to
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