SML3501
Dehydrocorydaline
≥98% (HPLC)
Synonym(s):
13-Methylpalmatine, 5,6-Dihydro-2,3,9,10-tetramethoxy-13-methyldibenzo[a,g]quinolizinium
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About This Item
Empirical Formula (Hill Notation):
C22H24NO4
CAS Number:
Molecular Weight:
366.43
UNSPSC Code:
41115709
NACRES:
NA.77
MDL number:
InChI
1S/C22H24NO4/c1-13-15-6-7-18(24-2)22(27-5)17(15)12-23-9-8-14-10-19(25-3)20(26-4)11-16(14)21(13)23/h6-7,10-12H,8-9H2,1-5H3/q+1
SMILES string
CC1=C2[N+](CCC3=C2C=C(OC)C(OC)=C3)=CC4=C(OC)C(OC)=CC=C41
InChI key
RFKQJTRWODZPHF-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
-10 to -25°C
Quality Level
Biochem/physiol Actions
Alkaloidal isolated from Rhizoma corydalis that exhibits anti-inflammatory, antinociceptive and anti-tumor effects
Dehydrocorydaline is an alkaloidal isolated from Rhizoma corydalis that exhibits anti-inflammatory, antinociceptive and anti-tumor effects. Dehydrocorydaline attenuates bone cancer pain through suppression M1 phenotype and upregulation M2 phenotype of microglia in the spinal cord.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Dehydrocorydaline attenuates bone cancer pain by shifting microglial M1/M2 polarization toward the M2 phenotype.
Huo W, Zhang Y, Liu Y, Lei Y, Sun R, Zhang W, Huang Y, Mao Y, Wang C, Ma Z, Gu X.
Molecular Pain (2018)
Zhi-Yu Yin et al.
Scientific reports, 6, 27129-27129 (2016-06-09)
Dehydrocorydaline (DHC) is an alkaloidal component isolated from Rhizoma corydalis. Previous studies have shown that DHC has anti-inflammatory and anti-tumor effects and that it can protect the cardiovascular system. However, there are few studies of the antinociceptive effects of DHC
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