SML3570
M4K2234NC
≥98% (HPLC)
Synonym(s):
(2-Fluoro-4-(5-(4-(4-isopropylpiperazin-1-yl)phenyl)-4-methylpyridin-3-yl)-6-methoxyphenyl)(pyrrolidin-1-yl), M4K2234 inactive control, M4K2234 negative control
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About This Item
Empirical Formula (Hill Notation):
C31H37FN4O2
Molecular Weight:
516.65
UNSPSC Code:
12352200
NACRES:
NA.77
InChI key
WFJOMSKCDAOJBT-UHFFFAOYSA-N
SMILES string
CC(C)N1CCN(CC1)C2=CC=C(C3=C(C)C(C4=CC(OC)=C(C(N5CCCC5)=O)C(F)=C4)=CN=C3)C=C2
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear (Warmed)
storage temp.
2-8°C
Quality Level
Related Categories
Biochem/physiol Actions
Inactive analog of and negative control for the potent and selective TGF-β type I receptors ALK1/ACVRL1 & ALK2/ACVR1 inhibitor M4K2234.
M4K2234NC is an inactive analog of and the recommended negative control for the potent and selective TGF-β type I receptors ALK1/ACVRL1 & ALK2/ACVR1 inhibitor M4K2234 (ALK1/2 IC50 >10 μM/ 5.69 μM by cellular NanoBRET assays; IC50 = 83 nM/13 nM using M4K2234).
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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