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SML3575

TY-51469

≥98% (HPLC)

Synonym(s):

2-[4-[[(5-Fluoro-3-methylbenzo[b]thien-2-yl)sulfonyl]amino]-3-(methylsulfonyl)phenyl]-4-thiazolecarboxylic acid, TY 51469

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About This Item

Empirical Formula (Hill Notation):
C20H15FN2O6S4
CAS Number:
603987-59-3
Molecular Weight:
526.60
UNSPSC Code:
12352200
NACRES:
NA.21
MDL number:
MFCD16628177
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

FC1=CC2=C(C=C1)SC(S(NC3=CC=C(C=C3S(C)(=O)=O)C4=NC(C(O)=O)=CS4)(=O)=O)=C2C

InChI key

CBRCULCCRGSSLB-UHFFFAOYSA-N

Biochem/physiol Actions

Potent and selective chymase inhibitor that prevents development and progression of non-alcoholic steatohepatitis in rats
TY-51469 is a potent and selective chymase inhibitor that prevents development and progression of non-alcoholic steatohepatitis in rats. TY-51469 inhibits activation of intestinal MMP-9 and prevents intestinal damage in indomethacin-induced small intestinal damage in rats. Also TY-51469 might protect against pancreatic islet disorganization.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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