Skip to Content
Merck
CN

SML3576

Mandipropamid

≥98% (HPLC)

Synonym(s):

(±)-Chlorophenyl)-N-[2-[3-methoxy-4-(prop-2-ynyloxy)phenyl]ethyl]-2-(prop-2-ynyloxy)acetamide, 4-Chloro-N-[2-[3-methoxy-4-(2-propyn-1-yloxy)phenyl]ethyl]-α-(2-propyn-1-yloxy)benzeneacetamide, Mandi

Sign In to View Organizational & Contract Pricing

Select a Size

About This Item

Empirical Formula (Hill Notation):
C23H22ClNO4
CAS Number:
374726-62-2
Molecular Weight:
411.88
MDL number:
MFCD09751510
UNSPSC Code:
12352200
NACRES:
NA.77

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Quality Level

100

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

-10 to -25°C

SMILES string

Clc1ccc(cc1)C(OCC#C)C(=O)NCCc2cc(c(cc2)OCC#C)OC

InChI

1S/C23H22ClNO4/c1-4-14-28-20-11-6-17(16-21(20)27-3)12-13-25-23(26)22(29-15-5-2)18-7-9-19(24)10-8-18/h1-2,6-11,16,22H,12-15H2,3H3,(H,25,26)

InChI key

KWLVWJPJKJMCSH-UHFFFAOYSA-N

Biochem/physiol Actions

Chemical inducers of proximity; specifically induces complex formation between PYR1 and ABI (Mandi CIP system); fungicide
Mandipropamid (Mandi) is an agrochemical extensively used as fungicide. Mandipropamid specifically induces complex formation between a sixfold mutant of the plant hormone receptor pyrabactin resistance 1 (PYR1) and abscisic acid insensitive (ABI). Mandipropamid is a highly cell permeable, low toxic chemical inducers of proximity in vivo. It induces rapid colocalization of proteins contained fused receptor domain PYRMandi and receiver domain ABI.

Pictograms

Environment
GHS09

Signal Word

Warning

Hazard Statements

H410

Precautionary Statements

P273 - P391 - P501

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

农药列管产品
This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0000220402
0000220403
0000220403
0000220402
0000209624

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Mandipropamid as a chemical inducer of proximity for in vivo applications
Nature Chemical Biology, 18, 64-69 (2022)
Agrochemical control of plant water use using engineered abscisic acid receptors
Nature, 520, 545-548 (2015)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service