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SML3579

Pyrimethamine

≥98% (HPLC)

Synonym(s):

2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidine, 5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidinediamine

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About This Item

Empirical Formula (Hill Notation):
C12H13ClN4
CAS Number:
58-14-0
Molecular Weight:
248.71
UNSPSC Code:
12352116
NACRES:
NA.21
MDL number:
MFCD00057350
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear (Wramed)

storage temp.

2-8°C

SMILES string

Clc1ccc(cc1)c2c(nc(nc2CC)N)N

InChI

1S/C12H13ClN4/c1-2-9-10(11(14)17-12(15)16-9)7-3-5-8(13)6-4-7/h3-6H,2H2,1H3,(H4,14,15,16,17)

InChI key

WKSAUQYGYAYLPV-UHFFFAOYSA-N

Biochem/physiol Actions

Antiparasitic inhibitor of dihydrofolate reductase; folic acid antagonist
Pyrimethamine is an antiparasitic drug used to treat malaria, toxoplasmosis and cystoisosporiasis. Pyrimethamine is a potent inhibitor of dihydrofolate reductase.

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pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

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