SML3582
TAM16
≥98% (HPLC)
别名:
5-Hydroxy-2-(4-hydroxyphenyl)-N-methyl-4-(1-piperidinylmethyl)-3-benzofurancarboxamide
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关于此项目
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
O=C(C1=C(OC2=CC=C(C(CN3CCCCC3)=C21)O)C4=CC=C(C=C4)O)NC
InChI
1S/C22H24N2O4/c1-23-22(27)20-19-16(13-24-11-3-2-4-12-24)17(26)9-10-18(19)28-21(20)14-5-7-15(25)8-6-14/h5-10,25-26H,2-4,11-13H2,1H3,(H,23,27)
InChI key
PQGCMFVNJWTUFH-UHFFFAOYSA-N
Biochem/physiol Actions
Potent and selective inhibitor of the thioesterase activity of Mycobacterium tuberculosis polyketide synthase Pks13
TAM16 is a potent and selective inhibitor of the thioesterase activity of Mycobacterium tuberculosis polyketide synthase Pks13. TAM16 is a highly potent bactericidal agent that exhibits activity against drug-susceptible and drug-resistant clinical isolates of M. tuberculosis. It is effective in both acute and chronic mouse TB models.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable