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SML3663

CAY10499

≥98% (HPLC)

Synonym(s):

CAY-10499, Benzyl 4-(5-methoxy-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-2-methylphenylcarbamate, CAY 10499, LEI 103, LEI-103, LEI103, Phenylmethyl N-[4-(5-methoxy-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-2-methylphenyl]carbamate, [4-(5-Methoxy-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-2-methylphenyl]-carbamic acid phenylmethyl ester

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About This Item

Empirical Formula (Hill Notation):
C18H17N3O5
CAS Number:
359714-55-9
Molecular Weight:
355.34
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
MFCD12912259
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

Biochem/physiol Actions

CAY10499 is a potent inhibitor against fatty acid amide hydrolase, hormone-sensitive lipase, and monoglyceride lipase (FAAH/HSL/MGL(MAGL) IC50 = 86/90/92 nM). Note: CAY10499 is reported to be irreversible by Muccioli et al. (PMID 18855964) and reversible by Minkkila et al. (PMID 19472270). Reported IC50 values vary depending greatly on pre-incubation time, substrates, enzyme source, as well as other experimental parameters employed.
Potent inhibitor against fatty acid amide hydrolase (FAAH), hormone-sensitive lipase (HSL), and monoglyceride lipase (MAGL, MGL).

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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