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SML3681

ATM-3507

≥95% (HPLC)

Synonym(s):

ATM 3507, [3-​[[2,​3-​Dimethyl-​1-​[3-​(4-​methyl-​1-​piperazinyl)​propyl]​-​1H-​indol-​5-​yl]​oxy]​phenyl]​[4-​[2-​(4-​fluorophenyl)​ethyl]​-​1-​piperazinyl]​-methanone

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About This Item

Empirical Formula (Hill Notation):
C37H46FN5O2
CAS Number:
1861449-70-8
Molecular Weight:
611.79
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
MFCD31657327
Assay:
≥95% (HPLC)
Form:
powder
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Quality Segment

100

assay

≥95% (HPLC)

form

powder

color

, Colorless to light brown

solubility

DMSO: 2 mg/mL, clear

storage temp.

-10 to -25°C

Biochem/physiol Actions

Potent anti-tropomyosin agent that disables Tpm3.1 containing actin filaments
ATM-3507 is a potent anti-tropomyosin agent that disables Tpm3.1 containing actin filaments. It exhibits potent cytotoxic activity against multiple neuroblastoma cancer cell lines. ATM-3507 sensitizes cancer cells to anti-microtubule agents. ATM-3507 significantly prolonged mitotic arrest induced by anti-microtubule agent vinorelbine.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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