SML3683
HHV maturational protease inhibitor 43
≥97% (1H-NMR)
Synonym(s):
(1-(3-Chloro-2-oxopropyl)-4-phenyl-1H-1,2,3-triazol-5-yl)methyl benzylcarbamate, HHV inhibitor 43
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About This Item
Empirical Formula (Hill Notation):
C20H19ClN4O3
Molecular Weight:
398.84
NACRES:
NA.77
UNSPSC Code:
51111800
assay
≥97% (1H-NMR)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
Quality Level
Related Categories
Biochem/physiol Actions
Covalent inhibitor of human herpesviruses (HHV) maturational protease.
HHV maturational protease inhibitor 43 is a cell penetrant, potent and selective covalent inhibitor of human herpesviruses (HHV) maturational protease that binds to non-catalytic Cysteine 161 adjacent to the protease active site. HHV maturational protease Inhibitor 43 disrupts HCMV (human cytomegalovirus) replication and infectivity. It can be used for managing human herpesviruses (HHV) infection.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Inhibiting a dynamic viral protease by targeting a non-catalytic cysteine
Cell Chemical Biology, 29(5), 785-798 (2022)
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