Quality Segment
assay
≥95% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear (Warmed)
shipped in
dry ice
storage temp.
−70°C
Biochem/physiol Actions
Inhibitor of pre-mRNA splicing; potent antitumor agent.
FR901464 is a potent anticancer agent isolated from the culture broth of the bacterium Pseudomonas sp. 2663. The compound binds to the splicing factor 3b complex and inhibits pre-mRNA splicing. FR901464 causes cell cycle arrest at the G1 and G2/M phases.
FR901464 is a potent anticancer agent isolated from the culture broth of the bacterium Pseudomonas sp. 2663. The compound binds to the splicing factor 3b complex and inhibits pre-mRNA splicing. FR901464 causes cell cycle arrest at the G1 and G2/M phases.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable