SML3714
SMIP004-7
≥98% (HPLC)
别名:
2-Methyl-4-butylaniline, 4-Butyl-2-methylaniline, 4-Butyl-2-methylbenzenamine
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关于此项目
经验公式（希尔记法）:
C11H17N
化学文摘社编号:
分子量:
163.26
UNSPSC Code:
12352200
NACRES:
NA.21
MDL number:
Assay:
≥98% (HPLC)
Form:
(Oil or liquid)
Quality Segment
assay
≥98% (HPLC)
form
(Oil or liquid)
color
colorless to brown
storage temp.
-10 to -25°C
SMILES string
Nc1c(cc(cc1)CCCC)C
InChI key
JTXOXRXZCAMPHL-UHFFFAOYSA-N
Biochem/physiol Actions
SMIP004-7 is a cell penetrant, potent and selective ubiquinone uncompetitive inhibitor of mitochondrial Complex I (NADH:ubiquinone oxidoreductase). SMIP004-7 selectively binds to a distinct N-terminal region of Complex I catalytic subunit NDUFS2, which leads to rapid disassembly of Complex I. SMIP004-7 potently inhibits growth of triple-negative breast cancer xenografts in mice.
cell penetrant, potent and selective ubiquinone uncompetitive inhibitor of mitochondrial Complex I
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable