SML3740
PY-60
≥98% (HPLC), YAP1 signaling activator, powder
Synonym(s):
5-Phenyl-N-[3-(2-thiazolyl)propyl]-3-isoxazolecarboxamide
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About This Item
Empirical Formula (Hill Notation):
C16H15N3O2S
CAS Number:
Molecular Weight:
313.37
UNSPSC Code:
12352200
NACRES:
NA.21
MDL number:
Product Name
PY-60, ≥98% (HPLC)
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
-10 to -25°C
Quality Level
Related Categories
Biochem/physiol Actions
PY-60 is a potent and specific activator of the transcriptional coactivator Yes-associated protein 1 (YAP) signaling. It stimulates YAP-dependent expansion of epidermal keratinocytes in mouse. PY-60 binds directly to annexin A2 (ANXA2) causing its liberation and YAP activation.
potent and specific activator YAP that binds directly to annexin A2.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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