SML3763
HSL-IN-1
≥97% (NMR)
Synonym(s):
B-[5-Chloro-2-[[[6-[4-(trifluoromethyl)phenoxy]-3-pyridinyl]carbonyl]amino]phenyl]boronic acid
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About This Item
Empirical Formula (Hill Notation):
C19H13BClF3N2O4
CAS Number:
Molecular Weight:
436.58
UNSPSC Code:
51111800
NACRES:
NA.21
MDL number:
assay
≥97% (NMR)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
-10 to -25°C
Quality Level
Related Categories
Biochem/physiol Actions
HSL-IN-1 is an orally available, potent, and selective inhibitor of Hormone-sensitive lipase (HSL) that exhibits an antilipolytic effect on rats.
Orally available, potent, and selective inhibitor of Hormone-sensitive lipase (HSL)
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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The dysfunction of hormone-sensitive lipase induces lipid deposition and reprogramming of nutrient metabolism in fish
The British Journal of Nutrition, 130(4), 588-603 (2023)
Omega-6 highly unsaturated fatty acids in Leydig cells facilitate male sex hormone production
Communications biology, 5(1), 1001-1001 (2022)
Identification of a novel hormone sensitive lipase inhibitor with a reduced potential of reactive metabolites formation
Bioorganic & Medicinal Chemistry, 25(7), 2234-2243 (2017)
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