SML3767
AA-263
≥98% (HPLC)
Synonym(s):
2-Hydroxybenzaldehyde 2-(4-nitrophenyl)hydrazone, NSC 101540, Salicylaldehyde 4-nitrophenylhydrazone, o-Hydroxybenzaldehyde p-nitrophenylhydrazone
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About This Item
Empirical Formula (Hill Notation):
C13H11N3O3
CAS Number:
Molecular Weight:
257.24
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
, Faint orange to Red
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
[N+](=O)([O-])c1ccc(cc1)N\N=C\c2c(cccc2)O
InChI
1S/C13H11N3O3/c17-13-4-2-1-3-10(13)9-14-15-11-5-7-12(8-6-11)16(18)19/h1-9,15,17H/b14-9+
InChI key
VQIJGQPVYQKSSH-NTEUORMPSA-N
Biochem/physiol Actions
AA-263 is a cell penetrant, potent and selective ATF6 activator that corrects the trafficking, conformation, secretion, and function of AAT-Z. AA-263 increases AAT neutrophil elastase (NE) inhibitory activity, while reducing polymer accumulation for the majority of AATD (alpha-1 antitrypsin (AAT) causes AAT deficiency) variants.
Cell penetrant, potent and selective ATF6 activator that corrects the trafficking, conformation, secretion, and function of AAT-Z
wgk
WGK 3
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
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