SML3775
Desthiobiotin-Phenol
≥98% (HPLC), peroxidase sensitive probe, powder
Synonym(s):
(4R,5S)-N-[2-(4-Hydroxyphenyl)ethyl]-5-methyl-2-oxo-4-imidazolidinehexanamide, DBP, Desthiobiotin-Tyramide, N-(4-Hydroxyphenethyl)-6-((4R,5S)-5-methyl-2-oxoimidazolidin-4-yl)hexanamide, d-Desthiobiotin-Phenol
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About This Item
Empirical Formula (Hill Notation):
C18H27N3O3
CAS Number:
Molecular Weight:
333.43
UNSPSC Code:
12352200
NACRES:
NA.21
Product Name
Desthiobiotin-Phenol, ≥98% (HPLC)
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
-10 to -25°C
Quality Level
Related Categories
Biochem/physiol Actions
A peroxidase-sensitive desthiobiotin-phenol (DBP) probe that offers more efficient recovery of DBP-labeled peptides from streptavidin beads and stronger mass spectrometry intensity of modified membrane proteins and achieves greater sensitivity for tyrosine residues detection. DBP shows a similar reactivity to the protein when it is converted to the phenoxyl radical state as biotin-phenol/biotin-tyramide (BP) in ascorbate peroxidase (APEX) proximity labeling. DBP exhibits reduced affinity to streptavidin and does not suffer from sulfur oxidation issue during the radical generation.
APEX (ascorbate peroxidase) proximity tyrosine site label, a sulfur-free Biotin-Tyramide analog that can be displaced competitively by biotin
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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