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Merck
CN

SML3779

Methotrexate disodium salt

≥98% (HPLC)

Synonym(s):

Amethopterin sodium, N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid disodium salt, Sodium methotrexate

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About This Item

Empirical Formula (Hill Notation):
C20H20N8Na2O5
CAS Number:
Molecular Weight:
498.40
UNSPSC Code:
12352200
NACRES:
NA.21
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
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Quality Segment

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to brown

solubility

H2O: 2 mg/mL, clear

storage temp.

-10 to -25°C

SMILES string

[Na].[Na].N([C@@H](CCC(=O)O)C(=O)O)C(=O)c1ccc(cc1)N(Cc2nc3c(nc(nc3N)N)nc2)C

InChI key

HQRCOVOSZPGUCA-GXKRWWSZSA-N

Biochem/physiol Actions

Folic acid antagonist that is used as an antineoplastic and antirheumatic drug
Methotrexate disodium salt is a potent is a folic acid antagonist that is used as an antineoplastic and antirheumatic drug. Methotrexate disodium salt is a potent inhibitor of dihydrofolate reductase.

Disclaimer

Hygroscopic


pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Muta. 2 - Repr. 1B - Skin Irrit. 2

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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