SML3786
Polaprezinc
≥97% (Zinc Elemental Analysis)
Synonym(s):
(N-(3-aminopropionyl)-L-histidinato zinc, N-β-Alanyl- L-histidine zinc complex, Zinc L-carnosine, beta-alanyl-L-histidinato zinc
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About This Item
Empirical Formula (Hill Notation):
C9H12N4O3Zn
CAS Number:
Molecular Weight:
289.61
UNSPSC Code:
12352200
NACRES:
NA.21
InChI key
IGXZLYMCFZHNKW-FJXQXJEOSA-L
SMILES string
[Zn]1N([C@H](C(=O)O1)Cc2[nH]cnc2)C(=O)CCN
assay
≥97% (Zinc Elemental Analysis)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
-10 to -25°C
Quality Level
Biochem/physiol Actions
Mucosal protective agent that exhibits ROS-quenching activities; stimulates Hsp70 expression
Polaprezinc is an orally available Zinc L-carnosine complex. It is a mucosal protective agent that exhibits ROS-quenching activities, which promotes the repair of damaged tissues. Polaprezinc exerts cytoprotection through stimulation of Hsp70 expression that prevents the development of inflammatory process in the large intestinal mucosa. It is approved in Japan and Korea for treatment of gastric ulcers.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Find documentation for the products that you have recently purchased in the Document Library.
Role of nutritional zinc in the prevention of osteoporosis
Molecular and Cellular Biochemistry, 338(1-2), 241-254 (2010)
Drug repositioning of polaprezinc for bone fracture healing
Communications biology, 5(1), 462-462 (2022)
Antioxidant, Anti-inflammatory, and Genomic Stability Enhancement Effects of Zinc l-carnosine: A Potential Cancer Chemopreventive Agent
Nutrition and Cancer, 69(2), 201-210 (2017)
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