SML3789
MS67
≥98% (HPLC)
Synonym(s):
N-(2′-fluoro-5′-((2-(((S)-1-((2S,4R)-4-hydroxy-2-(((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)carbamoyl)pyrrolidin-1-yl)-3,3dimethyl-1-oxobutan-2-yl)amino)-2-oxoethyl)carbamoyl)-4-((3S,5R)-3,4,5-trimethylpiperazin-1-yl)-[1,1′-biphenyl]-3-yl)-6-oxo 4-(trifluoromethyl)-1,6-dihydropyridine-3-carboxamide
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About This Item
Empirical Formula (Hill Notation):
C52H59F4N9O7S
CAS Number:
Molecular Weight:
1030.14
NACRES:
NA.21
UNSPSC Code:
12352200
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
-10 to -25°C
Biochem/physiol Actions
Cell penetrant, potent and selective WD40 repeat domain protein 5 (WDR5) degrader
MS67 is a cell penetrant, potent and selective WD40 repeat domain protein 5 (WDR5) degrader that effectively and selectively degrades WDR5 in human MLL-r AML and PDAC cells.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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