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About This Item
Empirical Formula (Hill Notation):
C25H26N6O
CAS Number:
Molecular Weight:
426.51
MDL number:
NACRES:
NA.28
SMILES string
C(N=C1C2=CCOCC2)(C3=CN(N=C3)C4CCNCC4)=CN5C1=NC(C6=CC=CC=C6)=C5
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear (Warmed)
storage temp.
room temp
Quality Level
Biochem/physiol Actions
Cell penetrant, potent and selective ferroptosis inhibitor that targets prohibitin 2 (PHB2).
YL-939 is a cell penetrant, potent and selective ferroptosis inhibitor. YL-939 binds directly to prohibitin 2 (PHB2) hence promoting the expression of the iron storage protein ferritin thus reducing the iron content, thereby decreasing the susceptibility to ferroptosis. YL-939 effectively protects cells from ferroptosis.
YL-939 is a cell penetrant, potent and selective ferroptosis inhibitor. YL-939 binds directly to prohibitin 2 (PHB2) hence promoting the expression of the iron storage protein ferritin thus reducing the iron content, thereby decreasing the susceptibility to ferroptosis. YL-939 effectively protects cells from ferroptosis.
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