SML3819
UNC-CA157
≥98% (HPLC)
Synonym(s):
4-((3,4,5-Trimethoxyphenyl)amino)quinoline-7-carbonitrile, 4-[(3,4,5-Trimethoxyphenyl)amino]-7-quinolinecarbonitrile
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About This Item
Empirical Formula (Hill Notation):
C19H17N3O3
CAS Number:
Molecular Weight:
335.36
NACRES:
NA.77
UNSPSC Code:
12352200
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
Quality Level
Related Categories
Biochem/physiol Actions
Cell penetrant, selective and potent inhibitor of archetypal UbiB protein COQ8.
UNC-CA157 is a cell penetrant, selective and potent inhibitor of COQ8 the member of archetypal UbiB family of atypical kinases (protein kinase-like (PKL) family). UNC-CA157 inhibits CoQ production in COQ8BKO cells.
UNC-CA157 is a cell penetrant, selective and potent inhibitor of COQ8 the member of archetypal UbiB family of atypical kinases (protein kinase-like (PKL) family). UNC-CA157 inhibits CoQ production in COQ8BKO cells.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Small-molecule inhibition of the archetypal UbiB protein COQ8
Nature Chemical Biology, 19(2), 230-238 (2023)
Identification and Optimization of 4-Anilinoquinolines as Inhibitors of Cyclin G Associated Kinase
ChemMedChem, 13(1), 48-66 (2018)
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