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SML3823

KCI807

≥98% (HPLC)

Synonym(s):

5,3’-Dihydroxyflavone, 5-Hydroxy-2-(3-hydroxyphenyl)-4H-1-benzopyran-4-one

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About This Item

Empirical Formula (Hill Notation):
C15H10O4
CAS Number:
6665-68-5
Molecular Weight:
254.24
UNSPSC Code:
51111800
NACRES:
NA.77
MDL number:
MFCD00143394
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

0.2 mg/mL (DMSO:EtOH (2:1),clear, warmed, clear colorless solution)

storage temp.

room temp

SMILES string

[o]1c2c([c](cc1c3cc(ccc3)O)=O)c(ccc2)O

InChI key

SZMQXDYEGKRZDG-UHFFFAOYSA-N

Biochem/physiol Actions

Cell penetrant, selective and potent inhibitor of the androgen receptor (AR)-ELK1 interaction
KCI807 is a cell penetrant, selective and potent inhibitor of the androgen receptor (AR)-ELK1 interaction. KCI807 interrupts association of the androgen receptor (AR) with transcription activator ELK1 (ETS family transcription factor ELK1). It potently suppresses growth of enzalutamide-resistant prostate cancer tumor xenografts in rodents.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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