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About This Item
Empirical Formula (Hill Notation):
C63H113N11O12
CAS Number:
Molecular Weight:
1216.64
UNSPSC Code:
51111800
NACRES:
NA.77
InChI key
OLROWHGDTNFZBH-XEMWPYQTSA-N
SMILES string
N1([C@H](C(=O)N[C@H](C(=O)N([C@@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C1=O)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)C(C)C)CC)C)C)CC)[C@H](O)[C@@H](C\C=C\C)C)C
assay
≥95% (HPLC)
form
(Powder or Lyophilized powder or film)
color
white to off-white
storage temp.
-10 to -25°C
Quality Level
Related Categories
Biochem/physiol Actions
Alisporivir is a Cyclophilin A inhibitor with potent anti-hepatitis C virus (HCV) activity. Alisporivir has also been investigated for Duchenne muscular dystrophy.
Cyclophilin A inhibitor; anti-viral with potent anti-hepatitis C virus (HCV) activity
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
常规特殊物品
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DEB025 (Alisporivir) inhibits hepatitis C virus replication by preventing a cyclophilin A induced cis-trans isomerisation in domain II of NS5A
PLoS ONE, 5(10) (2010)
Combating Intracellular Pathogens with Repurposed Host-Targeted Drugs
ACS infectious diseases, 4(2), 88-92 (2018)
Alisporivir rescues defective mitochondrial respiration in Duchenne muscular dystrophy
Pharmacological Research, 125(Pt B), 122-131 (2017)
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