SML3873
Pip6 PARP-1 inhibitor
≥98% (HPLC)
别名:
(S)-4-(3-(3-(1,1-difluoroethyl)-6-methyl-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine-7-carbonyl)-4-fluorobenzyl)phthalazin-1(2H)-one
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关于此项目
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
-10 to -25°C
Biochem/physiol Actions
Cell penetrant and potent inhibitor of PARP-1 that exhibits potent cytotoxicity in cancer cells.
Pip6 is a cell penetrant and potent inhibitor of PARP-1 (Poly (ADP-ribose) polymerase 1) that exhibits potent cytotoxicity in cancer cells. It appears that Pip6 improved cytotoxicity is due to enhanced target residence time on PARP-1.
Pip6 is a cell penetrant and potent inhibitor of PARP-1 (Poly (ADP-ribose) polymerase 1) that exhibits potent cytotoxicity in cancer cells. It appears that Pip6 improved cytotoxicity is due to enhanced target residence time on PARP-1.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable