Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
OC1=NC2=NON=C2C=C1NC3=C(C(F)=C(C(F)=C3F)F)F
Biochem/physiol Actions
Orally active mitochondria uncoupler that increases the energy expenditure and lowers the body fat mass in vivo.
SHM115 is an orally active mitochondria uncoupler (EC50 = 17 μM; measured as oxygen consumption rate (OCR) increase in L6 rat myoblast cells) that increases the energy expenditure and lowers the body fat mass in two diet-induced obesity mouse models, including an obesity prevention model (130 mg/kg/d via chow) and an obesity reversal model (130 mg/kg/d via oral gavage).
SHM115 is an orally active mitochondria uncoupler (EC50 = 17 μM; measured as oxygen consumption rate (OCR) increase in L6 rat myoblast cells) that increases the energy expenditure and lowers the body fat mass in two diet-induced obesity mouse models, including an obesity prevention model (130 mg/kg/d via chow) and an obesity reversal model (130 mg/kg/d via oral gavage).
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable