SML3877
SRI-32743
≥98% (HPLC)
别名:
2-(7-Methylimidazo[1,2-a]pyridin-6-yl)-N-(2-phenylbutyl)-4-quinazolinamine
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Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear (Warmed)
storage temp.
2-8°C
Biochem/physiol Actions
Allosteric modulator of monoamine transporters that acts as partial antagonists of dopamine uptake.
SRI-32743 is an allosteric modulator of monoamine transporters that acts as partial antagonists of dopamine uptake. SRI-32743 attenuates Tat (the HIV regulatory protein transactivator of transcription) induced inhibition of DAT-mediated dopamine uptake. Also, it alleviates the potentiation of cocaine reward in HIV-1 Tat transgenic mice.
SRI-32743 is an allosteric modulator of monoamine transporters that acts as partial antagonists of dopamine uptake. SRI-32743 attenuates Tat (the HIV regulatory protein transactivator of transcription) induced inhibition of DAT-mediated dopamine uptake. Also, it alleviates the potentiation of cocaine reward in HIV-1 Tat transgenic mice.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable