SML3920
Q275
≥98% (HPLC)
Synonym(s):
2-[(2-Hydroxyphenyl)amino]-5-(2-methyl-3-phenyl-2-propen-1-ylidene)-4(5H)-thiazolone
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About This Item
Empirical Formula (Hill Notation):
C19H16N2O2S
CAS Number:
Molecular Weight:
336.41
NACRES:
NA.77
UNSPSC Code:
51111800
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
Quality Level
Related Categories
Biochem/physiol Actions
Potent, bacterial specific allosteric inhibitor of mitochondrial heme-copper oxidase (HCO).
Q275 is a potent, bacterial specific allosteric inhibitor of mitochondrial heme-copper oxidase (HCO). Q275 is an effective antibiotic against ceftriaxone-resistant Neisseria gonorrhoeae. Q275 does not affect the cellular respiration of mammalian cells.
Q275 is a potent, bacterial specific allosteric inhibitor of mitochondrial heme-copper oxidase (HCO). Q275 is an effective antibiotic against ceftriaxone-resistant Neisseria gonorrhoeae. Q275 does not affect the cellular respiration of mammalian cells.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Identifying antibiotics based on structural differences in the conserved allostery from mitochondrial heme-copper oxidases
Nature Communications, 13(1), 7591-7591 (2022)
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