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Merck
CN

SML3932

DC-Y13-27

≥98% (HPLC)

Synonym(s):

(E)-2-cyano-3-(5-(3-hydroxyphenyl)thiophen-2-yl)acrylamide

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About This Item

Empirical Formula (Hill Notation):
C14H10N2O2S
Molecular Weight:
270.31
UNSPSC Code:
12352200
NACRES:
NA.21
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 30 mg/mL, clear

storage temp.

room temp

SMILES string

NC(/C(C#N)=C/C1=CC=C(C2=CC=CC(O)=C2)S1)=O

InChI key

FCXTXGWIQGHISV-JXMROGBWSA-N

Biochem/physiol Actions

Cell penetrant and specific inhibitor of an m6A reader YTHDF2.



DC-Y13-27 is a cell penetrant and specific inhibitor of an m6A reader YTHDF2 that overcomes MDSC(myeloid-derived suppressor cell)-induced immunosuppression and enhances combined IR and/or anti-PD-L1 treatment.


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signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable



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