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Merck
CN

SML3933

CLC-2 channel inhibitor, AK-42

≥98% (HPLC)

Synonym(s):

2-[[2,6-Dichloro-3-(phenylmethoxy)phenyl]amino]-3-pyridinecarboxylic acid, AK-42

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About This Item

Empirical Formula (Hill Notation):
C19H14Cl2N2O3
CAS Number:
Molecular Weight:
389.23
UNSPSC Code:
12352200
NACRES:
NA.21
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

-10 to -25°C

SMILES string

O=C(C1=C(NC2=C(Cl)C=CC(OCC3=CC=CC=C3)=C2Cl)N=CC=C1)O

InChI

1S/C19H14Cl2N2O3/c20-14-8-9-15(26-11-12-5-2-1-3-6-12)16(21)17(14)23-18-13(19(24)25)7-4-10-22-18/h1-10H,11H2,(H,22,23)(H,24,25)

InChI key

AYGDOYFDJDUPSS-UHFFFAOYSA-N

Biochem/physiol Actions

Specific and potent CLC-2 chloride channel inhibitor that binds to the CLC-2 channel extracellularly.



CLC-2 channel inhibitor AK-42 is a specific and potent CLC-2 chloride channel inhibitor that binds to the CLC-2 channel extracellularly. AK-42 causes selective and reversible blocking of CLC-2 currents.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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