SML3957
OSS_128167
≥98% (HPLC)
Synonym(s):
5-[[3-[(2-Furanylcarbonyl)amino]benzoyl]amino]-2-hydroxybenzoic acid
Sign In to View Organizational & Contract Pricing.
Select a Size
About This Item
Empirical Formula (Hill Notation):
C19H14N2O6
CAS Number:
Molecular Weight:
366.32
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
SMILES string
N(c2cc(ccc2)C(=O)Nc3cc(c(cc3)O)C(=O)O)C(=O)c1[o]ccc1
InChI
1S/C19H14N2O6/c22-15-7-6-13(10-14(15)19(25)26)20-17(23)11-3-1-4-12(9-11)21-18(24)16-5-2-8-27-16/h1-10,22H,(H,20,23)(H,21,24)(H,25,26)
InChI key
HTJWLEGCECXGSQ-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
-10 to -25°C
Quality Level
Related Categories
Biochem/physiol Actions
eCll penetrant, potent and selective inhibitor of SIRT6.
OSS_128167 is a cell penetrant, potent and selective inhibitor of SIRT6 (Sirtuin 6) that exhibits anti-cancer, anti-inflammatory, and anti-viral properties. OSS_128167 inhibits HBV transcription and replication through upregulating peroxisome proliferator-activated receptors α (PPARα) expression.
OSS_128167 is a cell penetrant, potent and selective inhibitor of SIRT6 (Sirtuin 6) that exhibits anti-cancer, anti-inflammatory, and anti-viral properties. OSS_128167 inhibits HBV transcription and replication through upregulating peroxisome proliferator-activated receptors α (PPARα) expression.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
新产品
This item has
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Discovery of novel and selective SIRT6 inhibitors
Journal of Medicinal Chemistry, 57(11), 4796-4804 (2014)
SIRT6 Inhibitor, OSS_128167 Restricts Hepatitis B Virus Transcription and Replication Through Targeting Transcription Factor Peroxisome Proliferator-Activated Receptors ?
Frontiers in Pharmacology, 10, 1270-1270 (2019)
Diosgenin protects against podocyte injury in early phase of diabetic nephropathy through regulating SIRT6
Phytomedicine, 104, 154276-154276 (2022)
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service