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SML3957

OSS_128167

≥98% (HPLC)

Synonym(s):

5-[[3-[(2-Furanylcarbonyl)amino]benzoyl]amino]-2-hydroxybenzoic acid

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About This Item

Empirical Formula (Hill Notation):
C19H14N2O6
CAS Number:
887686-02-4
Molecular Weight:
366.32
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
MFCD07114226
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

-10 to -25°C

SMILES string

N(c2cc(ccc2)C(=O)Nc3cc(c(cc3)O)C(=O)O)C(=O)c1[o]ccc1

InChI

1S/C19H14N2O6/c22-15-7-6-13(10-14(15)19(25)26)20-17(23)11-3-1-4-12(9-11)21-18(24)16-5-2-8-27-16/h1-10,22H,(H,20,23)(H,21,24)(H,25,26)

InChI key

HTJWLEGCECXGSQ-UHFFFAOYSA-N

Biochem/physiol Actions

eCll penetrant, potent and selective inhibitor of SIRT6.



OSS_128167 is a cell penetrant, potent and selective inhibitor of SIRT6 (Sirtuin 6) that exhibits anti-cancer, anti-inflammatory, and anti-viral properties. OSS_128167 inhibits HBV transcription and replication through upregulating peroxisome proliferator-activated receptors α (PPARα) expression.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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