SML3984
Insulin sensitizer, C59
≥98% (HPLC)
Synonym(s):
N-(4,5-Dichloro-2-pyridinyl)tricyclo[3.3.1.13,7]decane-1-carboxamide
Quality Level
Assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear (Warmed)
storage temp.
2-8°C
Biochem/physiol Actions
Orally available potentiator of insulin action that significantly improves glucose tolerance in DIO mice; restores insulin-stimulated GLUT4 translocation.
Insulin sensitizer C59 is an orally available potentiator of insulin action that significantly improves glucose tolerance in DIO mice. Insulin sensitizer C59 restores insulin-stimulated GLUT4 translocation without targeting PPARγ. It acts through interaction with Unc119 proteins. C59 lowers fasting blood glucose and plasma insulin concentrations in in DIO mice.
Insulin sensitizer C59 is an orally available potentiator of insulin action that significantly improves glucose tolerance in DIO mice. Insulin sensitizer C59 restores insulin-stimulated GLUT4 translocation without targeting PPARγ. It acts through interaction with Unc119 proteins. C59 lowers fasting blood glucose and plasma insulin concentrations in in DIO mice.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
新产品
This item has
Choose from one of the most recent versions:
Certificates of Analysis (COA)
Lot/Batch Number
Don't see the Right Version?
If you require a particular version, you can look up a specific certificate by the Lot or Batch number.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Terry C Yin et al.
Cell chemical biology, 30(8), 933-942 (2023-07-16)
Insulin resistance (IR) is the root cause of type II diabetes, yet no safe treatment is available to address it. Using a high throughput compatible assay that measures real-time translocation of the glucose transporter glucose transporter 4 (GLUT4), we identified
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service