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SML4000

MagZet1 Trifluoroacetate

≥90% (HPLC)

Synonym(s):

6-(Azetidin-1-yl)-4-chloroquinoline-2,8-dicarboxylic acid trifluoroacetate

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About This Item

Empirical Formula (Hill Notation):
C14H11ClN2O4 · xC2HF3O2
Molecular Weight:
306.70 (free base basis)
UNSPSC Code:
12352200
Assay:
≥90% (HPLC)
Form:
powder
Storage condition:
desiccated
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Quality Segment

assay

≥90% (HPLC)

form

powder

storage condition

desiccated

color

light orange to very dark red

solubility

H2O: 2 mg/mL, clear (warmed)

storage temp.

2-8°C

Biochem/physiol Actions

MagZet1 is a Mg2+ fluorescent sensor for the ratiometric detection of Mg2+ with good selectivity over Ca2+ (Kd = 140 µM/Mg2+ vs. 1.7 mM/Ca2+). At pH 7, MagZet1 shows Ex max/Em max/Φ of 490 nm/500 nm/40% in Mg2+-free and 395 nm/530 nm/76% in Mg2+-saturated form. Note: MagZet1 exhibits high affinity for Zn2+ (Kd = 2.6 nM), which is not expected to interfere with Mg2+ detection due to the typical low basal Zn2+ concentrations in cells (0.01 - 0.1 nM). Care should be taken, however, when the sensor is to be employed in Zn2+-rich samples. For detection: 405 nm excitation laser, emission 470-520 nm for the Mg2+-free form and 520-582 nm for the Mg2+-bound sensor.

Disclaimer

Hygroscopic, store with desiccant


Storage Class

11 - Combustible Solids

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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