SML4017
DiFMU
≥98% (HPLC)
Synonym(s):
6,8-Difluoro-7-hydroxy-4-methyl-2H-1-benzopyran-2-one, 6,8-Difluoro-7-hydroxy-4-methylcoumarin, Marina Blue
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About This Item
Empirical Formula (Hill Notation):
C10H6F2O3
CAS Number:
Molecular Weight:
212.15
UNSPSC Code:
12352200
MDL number:
NACRES:
NA.21
Quality Level
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
FC1=C2C(C(C)=CC(O2)=O)=CC(F)=C1O
InChI key
LLENVBUPWUQAGL-UHFFFAOYSA-N
Biochem/physiol Actions
Fluorescent product of hydrolysis of fluorogenic phosphatase substrate DiFMUP.
DiFMU is a fluorescent product of hydrolysis of fluorogenic phosphatase substrate DiFMUP. DiFMU excitation wavelength is 358nm and emission can be detected at 455 nm.
DiFMU is a fluorescent product of hydrolysis of fluorogenic phosphatase substrate DiFMUP. DiFMU excitation wavelength is 358nm and emission can be detected at 455 nm.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Skin Sens. 1
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Yue Ge et al.
Analytical biochemistry, 362(1), 63-68 (2007-01-24)
We describe a fluorescence-based assay for the analysis of xylanase activity using a novel fluorogenic substrate, 6,8-difluoro-4-methylumbelliferyl beta-D-xylobioside (DiFMUX(2)). Generation of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) from the substrate corresponded directly to xylanase activity. High-performance liquid chromatography analysis of the digestion products
Stefan Welte et al.
Analytical biochemistry, 338(1), 32-38 (2005-02-15)
The fluorogenic substrate 6,8-difluoro-4-methylumbiliferyl phosphate (DIFMUP) has been widely used for the detection of serine and threonine phosphatase activities. Here we describe the use of this substrate for the characterization of protein tyrosine phosphatases (PTPs) and for the screening for
Lei Sun et al.
Biomolecules, 5(3), 1284-1301 (2015-07-02)
Protein phosphatase 2A (PP2A) is one of the most abundant intracellular serine/threonine (Ser/Thr) phosphatases accounting for 1% of the total cellular protein content. PP2A is comprised of a heterodimeric core enzyme and a substrate-specific regulatory subunit. Potentially, at least seventy
Global Trade Item Number
| SKU | GTIN |
|---|---|
| SML4017-5MG | 04065271240841 |
| SML4017-25MG | 04065271240834 |