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SML4047

MitoTEMPOL

≥97% (HPLC)

Synonym(s):

2,2,6,6-Tetramethyl-4-[[5-(triphenylphosphonio)pentyl]oxy]-1-piperidinyloxy bromide, 2,2,6,6-Tetramethyl-4-[5-(triphenylphosphonio)pentoxy]piperidin-1-oxybromide, Mito-TEMPOL

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About This Item

Empirical Formula (Hill Notation):
C32H42NO2P· Br
CAS Number:
1101113-39-6
Molecular Weight:
583.56
UNSPSC Code:
12352200
Assay:
≥97% (HPLC)
Form:
(Solid or Waxy semi-solid)
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Quality Segment

assay

≥97% (HPLC)

form

(Solid or Waxy semi-solid)

color

white to light orange

solubility

DMSO: 2 mg/mL, clear

storage temp.

-10 to -25°C

Biochem/physiol Actions

MitoTEMPOL is a mitochondria-targeting antioxidant composed of the piperidine nitroxide TEMPOL and the lipophilic triphenylphosphonium cation. MitoTEMPOL is more active toward ubiquinol in mitochondrial membranes than butylTEMPOL, TEMPO and TEMPOL. Systemic administration of mitotempol prevents the sustained elevations of blood pressure in rats exposed to intermittent hypoxia (IH) for 10 days (10 mg/kg, i.p.).

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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