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About This Item
Empirical Formula (Hill Notation):
C25H31FN4O3
CAS Number:
Molecular Weight:
454.54
NACRES:
NA.21
SMILES string
O=C(N1CC(C)C)N(CC2=CC=C(C=C2)C3=CC=C(C(CNC4CCOCC4)=N3)F)CC1=O
assay
≥95% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
Quality Level
Biochem/physiol Actions
Orally available potent and selective cannabinoid CB2 receptor agonist.
LEI-102 is orally available, highly potent and highly selective cannabinoid CB2 receptor agonist. LEI-102 attenuates cisplatin-induced nephrotoxicity in mice. LEI-102 did not generate CB1R-mediated CNS-side effects at doses up to 25mg/kg (p.o.) in mice model.
LEI-102 is orally available, highly potent and highly selective cannabinoid CB2 receptor agonist. LEI-102 attenuates cisplatin-induced nephrotoxicity in mice. LEI-102 did not generate CB1R-mediated CNS-side effects at doses up to 25mg/kg (p.o.) in mice model.
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