SML4048
LEI-102
≥95% (HPLC)
Synonym(s):
1-[[4-[5-Fluoro-6-[[(tetrahydro-2H-pyran-4-yl)amino]methyl]-2-pyridinyl]phenyl]methyl]-3-(2-methylpropyl)-2,4-imidazolidinedione
Quality Level
Assay
≥95% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
O=C(N1CC(C)C)N(CC2=CC=C(C=C2)C3=CC=C(C(CNC4CCOCC4)=N3)F)CC1=O
Biochem/physiol Actions
Orally available potent and selective cannabinoid CB2 receptor agonist.
LEI-102 is orally available, highly potent and highly selective cannabinoid CB2 receptor agonist. LEI-102 attenuates cisplatin-induced nephrotoxicity in mice. LEI-102 did not generate CB1R-mediated CNS-side effects at doses up to 25mg/kg (p.o.) in mice model.
LEI-102 is orally available, highly potent and highly selective cannabinoid CB2 receptor agonist. LEI-102 attenuates cisplatin-induced nephrotoxicity in mice. LEI-102 did not generate CB1R-mediated CNS-side effects at doses up to 25mg/kg (p.o.) in mice model.
Regulatory Information
新产品
This item has
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service